|
KMID : 0900920000240030231
|
|
Korean journal of Animal Reproduction
2000 Volume.24 No. 3 p.231 ~ p.239
|
|
|
Effects of Dioxin on the Body Weight, No. of Sperm, Motility, Testis and Organ Weight in Mice
|
|
Kim Sang-Keun
Kim Min-Soo
Nam Yoon-Yi
Hyun Byung-Hwa
|
|
|
Abstract
|
|
|
|
In this study, we observed the effects of dioxin on weights of body, testes and other organs, the number and motility of sperm in the a various dose after two days’ of administration in mice. Animals were treated with oral dose of dioxin 10, 20, 30, 40 mg/kg body weight, respectively. 1, After administration dioxin at doses of 10, 20, 30 and 40 mutextrm{g}/kg to the mice, the changes in body weights were 30.6 pm02.g~40.7 pm 3.9g and 30.8 pm4.1g~39.5g pm3.1 for 10 and 20mutextrm{g}/kg dosed group, 31.0 pm 3.5g ~ 39.0 pm 3.5g, 30.6 pm 3.4g~38.3 pm 4.0g for 30 and 40 mutextrm{g}/kg dosed group. The body weight of dioxin-administered group showed lower value when compared to 30.6 pm 2.8g ~ 44.5 pm 3.1g of which is control group’s. 2. After administration of dioxin at doses of 10, 20, 30 and 40 mutextrm{g}/kg to the mice, the increase in the number of WBC was prominent, but the increase in the number of RBC wasn’t significant, though the values of Hb, PCV, and PLT were higher than those of control group’s. 3. After administration of dioxin at doses of 10. 20, 30 and 40 mutextrm{g}/kg to the mice, the changes in sperm number were 112.5 pm 3.7~119.4 pm4.2 times 10^{6} mell, 103.9 pm3.8 ~ 110.2 pm 3.6 times 10^{6} mell, 97.5 pm 3.4 ~105.7 pm 4.4 times 10^{6} mell, 87.2 pm 3.7~98.5 pm 3.8 times 10^{6} mell, respectively. The sperm number of dioxin-administered group showed lower value than that of control group’s, which was 119.0 pm04.3 ~ 120.7 pm4.8 times 10^{6} mell. After administration of dioxin at doses of 10~40mutextrm{g}/kg to the mice, the sperm motility were 69.4pm 3.0 ~ 86.6 pm4.7%. The sperm motility of dioxin-administered group showed lower value than that of control group’s. 4. After administration of dioxin at doses of 10, 20, 30 and 40mutextrm{g}/kg to the mice, the organ weight of each dioxin-administered group’s was decreased a little compared to that of control group’s. 5. After administration of dioxin at doses of 10, 20, 30 and 40 mutextrm{g}/kg to the mice, the weights of spleen, kidneys, and liver showed increase a little.
|
|
|
KEYWORD
|
|
|
Dioxin, Body weight, No. of sperm, Motility, Testis weight
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|
|
|